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Πλοήγηση ανά Συγγραφέα "Hadzopoulou-Cladaras, M."

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    • Critical role of residues defining the ligand binding pocket in hepatocyte nuclear factor-4 alpha 

      Aggelidou, E.; Iordanidou, P.; Tsantili, P.; Papadopoulos, G.; Hadzopoulou-Cladaras, M. (2004)
      Hepatocyte nuclear factor-4alpha (HNF-4alpha), a member of the nuclear receptor superfamily, is a crucial regulator of a large number of genes involved in glucose, cholesterol, and fatty acid metabolism. Unlike other members ...

    • In vitro activity of dietary flavonol congeners against human cancer cell lines 

      Tsimplouli, C.; Demetzos, C.; Hadzopoulou-Cladaras, M.; Pantazis, P.; Dimas, K. (2012)
      Flavonoids have physiological activity and a variety of pharmacological properties, including anticancer activity in vitro, but structure-anticancer activity relationships are unclear. The objectives of this work were to ...

    • SAFB1 interacts with and suppresses the transcriptional activity of p53 

      Peidis, P.; Voukkalis, N.; Aggelidou, E.; Georgatsou, E.; Hadzopoulou-Cladaras, M.; Scott, R. E.; Nikolakaki, E.; Giannakouros, T. (2011)
      A significant amount of nuclear p53 is found associated with the nuclear matrix in cells that were exposed to genotoxic stress. In this study we identified Scaffold attachment factor B1 (SAFB1), a nuclear matrix-associated ...